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1st PharMetrX Symposium

Date & Time


Seminar Room "Limmringhausen" Maria in der Aue, In der Aue 1, 42929 Wermelskirchen

08:30 – 09:15Arrival
09:15 – 09:30Charlotte Kloft & Wilhelm Husinga
Welcome & Introduction
09:30 – 11:00Presentations by PharMetrX PhD students, Part I (25 min. + 20 min. discussion)
Valerie Nock: Characterising proliferation and differentiation processes in leucopoiesis following high-dose chemotherapy

Sathej Gopalakrishnan: Towards Integrating Viral Dynamic Models with Mutational trees learned from clinical data to predict in vivo HIV phenotypic abundance
11:00 – 11:30Coffee & Tea
11:30 – 13:00Presentations by PharMetrX PhD students, Part II (25 min. + 20 min. discussion)
Ronald Niebecker: Simulation-based Analysis: Importance of study design for characterisation of nonlinear pharmacokinetics in monoclonal antibodies

Ludivine Fronton: PBPK modelling of Monoclonal Antibodies Disposition: Towards a compromise between the integration of the current mechanistic knowledge and the need of simplified models
13:00 – 14:00Lunch
14:15 – 15:45Presentations by PharMetrX PhD students, Part III (25 min. + 20 min. discussion)
André Schäftlein: Analysis Approaches of Microdialysis Data - Population pharmacokinetics of levofloxacin in peripheral tissues

Alexander Solms: Using Population PBPK Modelling to interpret Population PK results exemplified for Levofloxacin in Plasma and Interstitial Fluid
15:45 – 16:15Coffee & Tea
16:15 – 17:30Meeting of the Steering Board and the I-Partner representatives
17:45 – 18:15Award of the PharMetrX certificates to the former PharMetrX PhD and External PhD Students:
Sabine Pilari, Monika Frank, Kirstin Thelen

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